Antiulcerogenic Effect of Camel Milk Against Ethanol Induced Gastric Ulcers in Rats

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چکیده

The effect of oral administration of raw camel milk (5 ml/kg b.wt.) on ethanol– and aspirin–induced gastric ulcers was tested in rats. Oral administration of camel milk in rats with ethanol–induced gastric ulcer, significantly (P < 0.05) redudced the number of long ulcers, average length of ulcers, ulcer index and the volume of gastric juice. The total protein was significantly (P < 0.05) increased and the pH of gastric juice was not significantly changed. The curative ratio was 70.70% in camel milk treated group compared to 45.12% in ranitidine-treated rats. Oral administration of camel milk in rats with aspirin–induced gastric ulcers exhibited, significantly (P < 0.05), same actions with curative ratio of 65.03% compared to 34.03% in ranitidine-treated rats. In conclusion a significant protective effect of camel milk against ethanol– and aspirin–induced gastric ulcers was reported in rats.

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تاریخ انتشار 2012